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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“We would be lost without Greeting Card Universe. What other greeting card company has endless selections, the added bonus of personalization and prices that cannot be beat. We highly recommend Greeting Card Universe to all those who are frustrated with the limited greeting card selections in brick-and-mortar stores.”
Kathryn - Nov 3rd, 2026
“I have used Greeting Card Universe (GCU) for quite some time. It is a pleasure to write a review for them. The website is the best of the sites I have seen, which are similar to GCU. I have found a card -- every time -- for-every- reason that I've needed. Thank you for the great card! Anthony”
Anthony - Nov 2nd, 2026
Cards per Page:
Cards: 4,861 Pages: 163
Most Popular Newest Show adult cards
Happy 65th Birthday Sister with Typewriter, Chicka…
Happy Birthday to My Wonderful Sister Watercolor B…
Best Sister Ever 57th Birthday Typography in Pink …
Best Sister Ever 62nd Birthday Typography in Pink …
Best Sister Ever 73rd Birthday Typography in Pink …
73rd Birthday for Sister, Pearls and Petals card
Tall Lady Bug Happy Birthday for Sister card
Custom Relative Birthday for Sister White Cosmos F…
Sister Birthday Wildflowers Mason Jar Florals card
For Sister 89th Birthday White Flowers card
68th Birthday for Sister, Pearls and Petals card
Birthdays Little Sister Footprint card
Happy Birthday For Sister -- Purple and Pink Orchi…
Sis, Solar System, Happy Birthday! card
Wishes for a Happy Birthday for a Little Sister, K…
Birthday for Little Sister Pictured Rock Park, Mic…
76th Happy Birthday Sister, Magnolia Blossom card
Happy Birthday Sister - a (wine) drop of birthday …
Hey, Little Sister, Today is a Great Day to Celebr…
Sister Birthday, Beautiful Pink Daisy card
For My Sister - Tulips - Happy Birthday card
For sister, Happy birthday with roses card
Hey, Big Sister, Today is a Great Day to Celebrate…
Birthday, Sister, Egret and Roses card
Best Sister Ever 20th Birthday Typography in Pink …
Best Sister Ever 21st Birthday Typography in Pink …
Happy Birthday for a Special Little Sister, Lady S…
Best Sister Ever 37th Birthday Typography in Pink …
Naughty Puppy Sleeping--Birthday for Big Sister ca…
Sister Birthday Beautiful Butterflies and Flowers …
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