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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“A wonderful selection of beautiful cards for all occasions. Personalizations come out perfect. Shipped quickly and with upmost care. Best place to order cards.”
June - Nov 2nd, 2026
“I have used Greeting Card Universe (GCU) for quite some time. It is a pleasure to write a review for them. The website is the best of the sites I have seen, which are similar to GCU. I have found a card -- every time -- for-every- reason that I've needed. Thank you for the great card! Anthony”
Anthony - Nov 2nd, 2026
Cards per Page:
Cards: 4,861 Pages: 163
Most Popular Newest Show adult cards
95th Birthday, Sister, Pink Rose card
Happy Birthday Sister Funny Cat Putting on Lots of…
Mole Planting Flower Happy Birthday for Sister Scr…
Sister Birthday Pretty Alpaca on Pink Pastel Art C…
Birthday Heart of Flowers for a Sweet Sister on he…
Happy Birthday Sister, hummingbird with bright jew…
Happy 66th Birthday, Sister, Monarch Butterfly car…
Birthday for Sister card
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Sister Birthday, Orang Utan Jokes card
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Little Sister, Happy Birthday!, Pink Poseys in Fra…
Sister Birthday, seaside scene card
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Have a HIPPY BIRTHDAY, Sister! card
Happy 50th Birthday for a Sister, Rudbeckia flower…
Happy Birthday for a Sister, Yellow-Orange Rose, c…
Pink Watercolor Roses Happy 65th Birthday Sister c…
Peach Floral Vintage Stripes Sister Birthday Card
Happy 82nd Birthday to a Special Sister, Orange fl…
Happy Birthday Amazing Awesome Sister Watercolor F…
Sister 70th Birthday Wildflowers Mason Jar Celebra…
Sister, Patchwork Stitch Effect Your Photo Birthda…
87th Happy Birthday Sister, Magnolia Blossom card
Birthday to Sister, Raccoons with party hats, colo…
Sister Birthday Love Customizable Hearts Design ca…
81st Birthday for Sister, Pearls and Petals card
Add a picture,Sister age 50, with pink rose and je…
Happy Birthday Sister Garden Flowers card
For Sister Birthday Greeting Card-Chocolate Cupcak…
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