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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“We would be lost without Greeting Card Universe. What other greeting card company has endless selections, the added bonus of personalization and prices that cannot be beat. We highly recommend Greeting Card Universe to all those who are frustrated with the limited greeting card selections in brick-and-mortar stores.”
Kathryn - Nov 3rd, 2026
“Greeting Card Universe is my go to for all my cards. They have a great selection for all occasions. I just got my sister a lovely birthday card for her 75th birthday and I like that I was able to edit the inside with my own personalized message. Good quality, always great and never lets me down.”
Nancy - Nov 2nd, 2026
Cards per Page:
Cards: 4,861 Pages: 163
Most Popular Newest Show adult cards
Happy 65th Birthday Sister Purple Flowers card
85th Birthday,Sister,Purple Helebore Flower card
55th birthday for sister, pearls and petals card
Sister Happy Birthday From Sister Beach Wine Cupca…
Happy 73rd Birthday for a Sister, Rudbeckia flower…
Happy Birthday to a Special Sister Female Motorcyc…
78th Happy Birthday Sister, Magnolia Blossom card
Sister Happy Birthday Beach Coastal Sea Glass Shel…
Birthday, Sister, Victorian Flare with Lace, Ribbo…
Butterfly Mirror Sister Birthday card
Big Sister, Happy Birthday, Acrostic Flowery Compl…
Happy Birthday to Little Sister Pretty Ballerina c…
Sister 30th Birthday Green Flowers card
Happy 40th Birthday Sister with Typewriter, Chicka…
Custom Relative Birthday for Sister Purple Thistle…
Cloud Palomino Birthday Card for Sister card
Happy 85th Birthday or a Stunning Sister, Purple A…
Best Sister Ever 16th Birthday Typography in Pink …
Birthday, Sister, Purple Iris in bowl card
Happy 30th Birthday to a Wonderful Little Sister, …
Best Sister Ever 25th Birthday Typography in Pink …
For Sister’s Birthday With Poppies Daisies and Cor…
Happy 68th Birthday, Sister, Monarch Butterfly car…
Happy 49th Birthday to a Wonderful Little Sister, …
Hand Lettered Birthday Sister Monthly September Mo…
Humorous Sister Birthday The Most Important Day Of…
Sister From Sister Birthday My Most Favorite And O…
Sister Birthday Scattered Leaves card
Birthday, Sister, Pink Gingham with Flowers and Mu…
Sister Happy Birthday Butterflies Flowers in Jars …
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