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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“I have given the GCU name to more than a few of people to whom I have sent your cards. I should be getting a commission for the business I send your way. EVERYONE loves your cards.”
Kathleen - Masonic Home, Kentucky - Nov 2nd, 2026
“Greeting Card Universe is my go to for all my cards. They have a great selection for all occasions. I just got my sister a lovely birthday card for her 75th birthday and I like that I was able to edit the inside with my own personalized message. Good quality, always great and never lets me down.”
Nancy - Nov 2nd, 2026
Cards per Page:
Cards: 4,861 Pages: 163
Most Popular Newest Show adult cards
Birthday, Sister, Black and White Layers of Differ…
Happy 83rd Birthday, Sister, Monarch Butterfly car…
Birthday to Sister Card with a Raccoon holding a B…
For Sister Birthday Card Bouquet of Flowers with B…
Sister Birthday Card - Humorous, Dog Sticking out …
Happy 69th Birthday or a Stunning Sister, Purple A…
Sister Happy Birthday Humor Funny with Two Owls Au…
Bubblebath Bear Happy Birthday Sister card
Happy 69th Birthday, Sister, Monarch Butterfly car…
Hey Sister, its Your 59th Birthday, Sea Shells and…
Retro Birthday Sister Mid Century Modern Pink Flam…
Sister Birthday with Flowering Tree and Party Bird…
Happy Birthday to Little Sister- Little Girl with …
Sister 16th Birthday with Crown and Gold Look Dots…
Happy Birthday, Sister, Petunias, Purple and White…
Happy Birthday To My Sister, two funny puffins car…
Fabulous Sister, Watercolor Floral Garden Scene Wi…
Birthday Heart of Flowers for a Sweet Sister on he…
Sister, 63rd, Happy Birthday, Mason Jar, Flowers, …
Sister, 66th, Happy Birthday, Mason Jar, Flowers, …
Happy 58th Birthday to a Special Sister, Orange fl…
Happy 66th Birthday Sister with Typewriter, Chicka…
Sister, 23rd, Happy Birthday, Mason Jar, Flowers, …
Happy Birthday to a Wonderful Big Sister, Orange f…
Sister, 92nd, Happy Birthday, Mason Jar, Flowers, …
Happy Birthday Sister card
Sister Birthday Cat Leaning on a Cupcake Sending L…
Best Sister Ever 69th Birthday Typography in Pink …
56th Happy Birthday Sister, Magnolia Blossom card
Happy Birthday Sister with Cake and Roses card
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