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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“I have given the GCU name to more than a few of people to whom I have sent your cards. I should be getting a commission for the business I send your way. EVERYONE loves your cards.”
Kathleen - Masonic Home, Kentucky - Nov 2nd, 2026
“I absolutely love Greeting Card Universe! It is so much fun being able to create the text of the cards you are buying. Price is another bonus, their cards are so reasonable. Also, Customer Service is outstanding and work with you perfectly. I recommend this business 100%”
Karen - Nov 1st, 2026
Cards per Page:
Cards: 4,835 Pages: 162
Most Popular Newest Show adult cards
For Sister on 70th Birthday Custom Japanese Anemon…
Happy Birthday Big Sister, pink flowers card
Cute grey bear popping out from Birthday present f…
Sister 50th Birthday Pink Teacup with Lily of the …
Happy June Birthday Sister Pink Rose Flower Waterc…
Happy Birthday, May Birthday for Sister card
Happy Birthday for Big Sister from Brother Boy and…
Happy Birthday to Little Sister- Little Brown Eyed…
Sister Happy Birthday Autumn Vibes Orange Yellow C…
Happy Birthday Sister December Holly Coffee card
Happy Birthday to Our Sister Party Cake card
Twin Sister Happy Birthday Pretty Princess with Pr…
Happy Birthday, Sister, Humor, Balloons,Catfucius,…
Happy Birthday Sister Beautiful Day for Birthday F…
Sister 60th Birthday - Cute Bunnies and Balloon ca…
For Sister 69th Birthday White Flowers card
81st Birthday, Sister, Pink Rose card
Birthday on Christmas Eve to Sister with Raccoons …
Happy Birthday to Sister from Sister Humorous Word…
Teddy Bear, Cupcake, Birthday for Sister, Customiz…
Sister 60th Birthday Yellow Roses with Monarch But…
Hey Sister, its Your 70th Birthday, Sea Shells and…
Birthday to Sister with a Border Collie Sitting in…
Pink Watercolor Roses Happy 70th Birthday Sister c…
Another Birthday a Prickly Subject for a Big Siste…
Happy Birthday for a Big Sister, Yellow-Orange Ros…
90th Happy Birthday Sister, Magnolia Blossom card
74th Birthday, Sister, Pink Rose card
Birthday, Sister, Daffodils in Blue & White Vintag…
Birthday to Sister Adult Humor with a Chalkboard a…
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