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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“I have given the GCU name to more than a few of people to whom I have sent your cards. I should be getting a commission for the business I send your way. EVERYONE loves your cards.”
Kathleen - Masonic Home, Kentucky - Nov 2nd, 2026
“I have used Greeting Card Universe (GCU) for quite some time. It is a pleasure to write a review for them. The website is the best of the sites I have seen, which are similar to GCU. I have found a card -- every time -- for-every- reason that I've needed. Thank you for the great card! Anthony”
Anthony - Nov 2nd, 2026
Cards per Page:
Cards: 4,840 Pages: 162
Most Popular Newest Show adult cards
Birthday for Little Sister - Little Angel Penguin …
46th Happy Birthday Sister, Magnolia Blossom card
Sister 38th Birthday Pink Teacup with Lily of the …
Sister Age 3 Teddy Bear card
35th birthday for sister, with a stitched flower c…
20th birthday for sister, pearls and petals card
25th birthday for sister, pearls and petals card
Sister Birthday Roses Painted Watercolor card
Happy Birthday, Sister! Red Flowers in a Blue Vase…
Sister 19th Birthday with Crown and Gold Look Dots…
Sister 37th Birthday Green Flowers card
27th Birthday, Sister, Pink Rose card
Birthday, Sister, Egret Birds card
Birthday, Sister, Red Rose, Stripes card
Birthday, sis card
Birthday, Sis card
Birthday, Sister, Little Blue Heron card
23rd Birthday, Sister, with Magnolia card
Birthday Wishes, Sis, two big bright green flowers…
Happy Birthday for Sister- Primitive Fairy with St…
Primitive Kitty- Birthday for Sister card
Happy Birthday for Sister- Harlequin card
Butterfly Whimsy Brithday Sister card
Flower Carnival Sister Birthday card
30th Birthday Purse for Sister card
Sister 9th Birthday Glittery Effect Butterflies an…
45th Happy Birthday Sister, Magnolia Blossom card
Sister 6th Birthday Glittery Effect Butterflies an…
Happy Birthday, A Little Birdie Told Me_Little Sis…
Sister Birthday Pretty Little Girl with Puppy card
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