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Birthday Cards for Sister

Browse our collection of birthday cards for sisters! What relationship in your life is more special than the one you share with your sister? No matter what stage of life you are both in, whether she is older, younger or even a twin, we have the perfect card to express your heartfelt birthday wishes. Our birthday cards for sisters cover the gamut from sweet and sentimental to funny and sarcastic.

We offer cards for milestone birthdays, pretty cards, sentimental cards, trendy cards, humorous cards and cards that can be customized to say just what you want. You can even add a picture to make your card truly one-of-a-kind. Don't settle for another generic card off the rack, create a personalized card that she'll cherish as a keepsake for years to come! Once you find the perfect birthday card for your sister, we'll print and mail it the next day!
Birthday Cards for Sister

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Shopper Testimonials
“I recently had an appointment with my doctor. She was tearful during the exam. The office help noticed and I chimed in. She began telling her story to me and I sent this card to cheer her up. I liked the inside message and front picture. I felt so happy. I was able to send this card to cheer her up a bit. She was going through a rough time personally. The card fit the situation. Paul Safran”
Paul - Camarillo, Ca. - Nov 1st, 2026
“We would be lost without Greeting Card Universe. What other greeting card company has endless selections, the added bonus of personalization and prices that cannot be beat. We highly recommend Greeting Card Universe to all those who are frustrated with the limited greeting card selections in brick-and-mortar stores.”
Kathryn - Nov 3rd, 2026
Cards per Page:
Cards: 4,840 Pages: 162
Most Popular Newest Show adult cards
Birthday, Sister, Ballerina in Arabesque Position …
Big Sister Birthday Young Girl in Balloons card
Happy Birthday Sister, Purple & Black Dragonflies …
Happy Birthday to My Wonderful Sister Watercolor E…
Happy 7th Birthday Sister Cute Girl with Animal Fr…
Sister’s Birthday Card with Mallard Duck card
Happy Birthday to My Big Sister It’s Your Day Cele…
Happy Birthday Sister 16 Floral Wreath Wildflowers…
Sister 17th Birthday Blue Crescent Moon and Stars …
Sister 5th Birthday Happy Birthday with Pretty Fai…
Happy Birthday Sis, yellow rose card
Sister’s Birthday-daisy bouquet in a black and whi…
Twin Sister’s Birthday - sneakers with daisy bouqu…
Big Sister 8th Birthday Cute Girl with Animal Frie…
Sister 24th Birthday Blue Crescent Moon and Stars …
Sister 29th Birthday Blue Crescent Moon and Stars …
Happy 13th Birthday Sister Floral Wreath Wildflowe…
Happy Birthday Sister Mountains Birds Clouds Sky L…
Sister’s birthday pink daisy in a frame card
Happy Birthday Sister card
For Sister 50th Birthday Custom Pink Hydrangea Flo…
For Sister on 20th Birthday Poppy Field Custom Lan…
Humorous Sister Birthday To The World’s Okayest Si…
For Sister on 15th Birthday Custom Lotus Fairy Wat…
For Sister 45th Birthday Custom Lake Buttermere Cu…
For Sister on 19th Birthday Custom Petunia Rose Wr…
Sister 13th Birthday with Crown and Gold Look Dots…
Sister 17th Birthday with Crown and Gold Look Dots…
Fifty Second Birthday Card Cartoon Bear My Sister’…
Birthday For Twin Sister Person Actually Remembere…
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